Portal hypertension from cirrhosis:
Caput medusae—abdominal skin
Life-threatening complications of Hepatic failure
Multiple organ failure
Esophageal varices, risk of rupture
Malignancy with chronic disease
Metaplasia (Greek: "change in form") is the reversible replacement of one differentiated cell type with another mature differentiated cell type.
Dysplasia (from the Greek δυσπλασία "malformation", δυσ- "mal-" + πλάθω "to create, to form"), is a term used in pathology to refer to an abnormality of development. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.
Anaplasia refers to a reversion of differentiation in cells and is characteristic of malignant neoplasms (tumors). Sometimes, the term also includes an increased capacity for multiplication. Lack of differentiation is considered a hallmark of malignancy.