Sunday, January 16, 2011

Disorders Associated with Splenomegaly.

I. Infections
Nonspecific splenitis of various blood-borne infections (particularly infective endocarditis)
Infectious mononucleosis
Tuberculosis
Typhoid fever
Brucellosis
Cytomegalovirus
Syphilis
Malaria
Histoplasmosis
Toxoplasmosis
Kala-azar
Trypanosomiasis
Schistosomiasis
Leishmaniasis
Echinococcosis

II. Congestive States Related to Portal Hypertension
Cirrhosis of the liver
Portal or splenic vein thrombosis
Cardiac failure

III. Lymphohematogenous Disorders
Hodgkin lymphoma
Non-Hodgkin lymphomas and lymphocytic leukemias
Multiple myeloma
Myeloproliferative disorders
Hemolytic anemias
Thromobocytopenic purpura

IV. Immunologic-Inflammatory Conditions
Rheumatoid arthritis
Systemic lupus erythematosus

V. Storage Diseases
Gaucher disease
Niemann-Pick disease
Mucopolysaccharidoses

VI. Miscellaneous
Amyloidosis
Primary neoplasms and cysts
Secondary neoplasm and metastasis.

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