Friday, January 14, 2011

Nasopharyngeal Carcinoma.

Associated with EBV infection

High incidence in chinese

Types:

keratinizing squamous cell carcinoma
nonkeratinizing squamous cell carcinoma
undifferentiated carcinoma

M/E large epithelial cells having indistinct cell borders ("syncytial" growth) and prominent eosinophilic nucleoli

in infectious mononucleosis, atypical lymphocytosis, seen in the peripheral blood, and enlarged lymph nodes are present- lymphocytes may invade the tumor too.

They tend to be radiosensitive
Nasopharyngeal angiofibroma is an important cause of epistaxis in the adolescent male- the tumor is testosterone dependent.

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