Hyperplastic Arteriolosclerosis

Morphology - concentric, onion skin thickening of walls of arterioles

Clinical significance - associated with malignant or accelerated hypertension

Pathogenesis - vasoconstriction


Hyperplastic Arteriolosclerosis. The renal artery at left has a concentric,
onion-skin-like thickening.


Kidney in malignant hypertension. It is atrophic, has irregular small infarcts, and a
more coarsely irregular cortical surface than in the arterionephrosclerosis seen earlier.