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Relative frequency of different breast carcinoma.

In Situ Carcinoma 15–30

Ductal carcinoma in situ 80
Lobular carcinoma in situ 20

Invasive Carcinoma 70–85

No special type carcinoma ("ductal")(NOS) 79
Lobular carcinoma 10
Tubular/cribriform carcinoma 6
Mucinous (colloid) carcinoma 2
Medullary carcinoma 2
Papillary carcinoma 1
Metaplastic carcinoma

A. Estrogen receptor is detected in the nucleus by immunohistochemical studies. Progesterone receptor has the same appearance.

B. HER2/neu overexpression is detected on the cell membrane by immunohistochemistry.

C. Amplification of the HER2/neu gene can be detected by FISH analysis