Friday, September 18, 2015

Common Causes of Anion gap metabolic acidosis

Common Causes of Anion gap metabolic acidosis:

1.Lactic acidosis: Hypoxia, poor tissue perfusion, mitochondrial dysfunction

2. Ketoacidosis: Type I diabetes, starvation or alcoholism

3. Methanol ingestion : Formic acid accumulation

4. Ethylene glycol ingestion : Glycolic and oxalic acid accumulation

5. Salicylate poisoning: Causes concomitant respiratory alkalosis

6. Uremia (ESRD): Failure to excrete H+ as NH4+

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